Children's Mercy KC

Post Doctoral Research Scholar- Dr.Elin Grundberg

Requisition ID
2020-13042
Requisition Post Information* : Posted Date
11 months ago(11/5/2020 7:42 AM)
Posting Category
Research
Division
START-UP DIV FUNDED
Shift
Day shift
Work Type
Full Time 60-80
Work Days
M-F
FLSA Status
Exempt
Location : Name
MAIN CAMPUS
Recruiter : Full Name: First Last
Julie Aust
Recruiter : Email
jaaust@cmh.edu

Thanks for your interest in Children's Mercy!

Do you envision finding a meaningful role with an inclusive and compassionate team? At Children’s Mercy, we believe in making a difference in the lives of all children and shining a light of hope to the patients and families we serve. Our employees make the difference, which is why we have been recognized by U.S. News & World Report as a top pediatric hospital, for eleven consecutive years.

 

Children’s Mercy is in the heart of Kansas City – a metro abounding in cultural experiences, vibrant communities and thriving businesses. This is where our patients and families live, work and play. This is a community that has embraced our hospital and we strive to say thanks by giving back. As a leader in children’s health, we engage in meaningful programs and partnerships throughout the region so that we can improve the lives of children beyond the walls of our hospital.

 

 

Overview

This is a two-year post-doctoral appointment (with possible renewal) to provide advance research training in genomic medicine to enhance the diversity of the research workforce at Children’s Mercy Research Institute by recruiting individuals from diverse backgrounds, including those from groups that have been shown to be underrepresented in health-related research areas. We are specifically looking for individuals with a doctoral degree in biological or computational sciences. This position is under the mentorship of Dr. Elin Grundberg-https://www.childrensmercy.org/profiles/elin-grundberg/

 

Founded in 2016, Children’s Mercy Research Institute (CMRI) was developed to transform the outstanding clinical care environment of Children’s Mercy Kansas City (CMKC) by integrating pediatric translational research. The goal of CMRI is to become a national leader in pediatric translational research over the next several years. To realize this goal, CMRI prioritized strategic investments to grow research capabilities focusing on our emerging strengths in Genomic Medicine, Precision Therapeutics, Health Outcomes and Innovation in Healthcare Delivery.

 

Children’s Mercy cares for more than 200,000 children each year, where many of the conditions encountered are disproportionally affecting children from racial and ethnic minoritized groups. One example of such condition is childhood asthma where African American/Black and Hispanic children are more likely to have a diagnosis of asthma and significantly higher asthma-related morbidity in comparisons with non-Hispanic white children. The cause of this health disparity is not clearly understood. Genetic factors alone or in combination with differences in environment exposures or lifestyle are important but have not been able to fully explain observed disparities. We hypothesize that psychosocial factors such as chronic stress experienced during childhood contribute to chronic respiratory disease risk among groups experiencing health disparities.

 

The study will use high-resolution epigenetic approaches at population and single-cell level to reveal epigenetic changes in immune cells predicting antiviral response and development of asthma. The goal is to combine population-based epigenome mapping in nasal mucosal samples with single immune cell analysis in large pediatric asthma cohorts of African American/Black children with detailed information about asthma, viral status and chronic stress exposures of several domains. The program will provide new insight into how genes and the social environment combine to influence heterogeneity in the response to environmental stressors and contribute to the health disparity seen in children with asthma.

 

We seek a highly motivated, team-oriented individual with good organizational, interpersonal, and communications skills to tackle challenges in next-generation epigenomics within a dynamic multi-disciplinary environment. The candidate will join a team of leading allergy/asthma/immunologist, behavioral scientist, epigeneticists, microbiologist and population geneticists leveraging multi-disciplinary expertise and resources to gain detailed insight into observed health disparity in childhood asthma. The position is located at the Center for Pediatric Genomic Medicine where successful candidates will have access to its state-of-the-art core facilities.

 

We particularly seek candidates from racial and ethnic groups which are underrepresented in biomedical research from the following groups: Black or African American, Hispanic or Latino, American Indian or Alaska Native, Native Hawaiian and other Pacific Islander.

 

At Children’s Mercy, we are committed to ensuring that everyone feels welcomed within our walls. A successful candidate for this position will join us as we strive to create a workplace that reflects the community we serve, as well as our core values of kindness, curiosity, inclusion, team and integrity.

 

 

Additionally, it’s important to us that we remain transparent with all potential job candidates. Because we value the safety of the patients and families we serve, as well as the Children’s Mercy staff, we want to let you know that the seasonal influenza and COVID-19 vaccines are a condition of employment for all employees in our organization. New employees must be willing to be vaccinated if found non-immune to measles, mumps, rubella (MMR) and chicken pox (varicella) and/or without evidence of tetanus, diphtheria, acellular pertussis (Tdap) vaccination since 2005. If you become a finalist for this position, and have any concerns about receiving these vaccines, medical and/or religious exemptions can be further discussed with Human Resources.

 

Responsibilities

 

  • Be responsible for the analysis of next-generation sequencing data (epigenetic) in integration with clinical information and social stress tests. Develop and/or implement bioinformatics, computational and statistical methods to support the data analysis.
  • Present research results at lab meetings and division meetings. Present at regional and national scientific conferences, publications of abstracts, and publication of research articles in peer-reviewed journals.
  • Attend/participate in mandatory educational programs, meetings and scholar conferences.

Qualifications

 

  • PhD or MD or related doctoral level degree in a relevant discipline
  • 1-year experience
  • Experience in application of statistical methods to the analysis of large-scale genetic/genomics data
  • A firm grounding in statistical and computational methods relevant to the analysis of NGS data
  • Preferable knowledge of other relevant subjects related to the project including epigenetics, immunology, asthma/allergy, virology and/or behavioral sciences

EEO Employer/Disabled/Vet

Children’s Mercy hires individuals based on their job skills, expertise and ability to maintain professional relationships with fellow employees, patients, parents and visitors. A personal interview, formal education and training, previous work experience, references and a criminal background investigation all are factors used to select the best candidates. The hospital does not discriminate against prospective or current employees based on the race, color, religion, sex, national origin, age, disability, creed, genetic information, sexual orientation, gender identity or expression, ancestry or veteran status. A drug screen will be performed upon hire. Children’s Mercy is smoke and tobacco free.

Our commitment to Diversity & Inclusion

CM is committed to creating a diverse and inclusive workforce. Our patients and families come from all walks of life, and so do we. We know that our greatest strengths come from the people who make up our team so we hire qualified people from a wide variety of backgrounds, not just because it’s the right thing to do, but because it makes our hospital stronger and our patient care more compassionate.

If you share our values and our enthusiasm for service, you will find a home at CM. In recruiting for our team, we welcome the unique contributions that you can bring, including education, ideas, culture, ethnicity, race, sex, sexual orientation, gender identity and expression, national origin, age, languages spoken, veteran status, color, religion, disability and beliefs.

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